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与B型大动脉剖析患者中胃肠道并发症相关的临床和财务结果
Troy N Coaston1, Amulya Vadlakonda1, Esteban Aguayo1
1Cardiac Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, CA, 90024, United States of America.
Surgery open science
|November 19, 2025
概括
在B型大动脉剖析患者中,胃肠道并发症显著增加了死亡率,停留时间和成本. 早期识别和有针对性的干预对这一高风险群体至关重要.
科学领域:
- 心血管外科心血管外科
- 胃肠病学 胃肠病学
- 卫生经济学 卫生经济学
背景情况:
- 胃肠道并发症 (GIC) 是B型大动脉剖析 (TBAD) 的罕见但严重的后果.
- 这些并发症可以显著增加死亡率和医疗保健资源利用率.
- 关于GIC在TBAD患者的临床和财务影响的研究有限.
研究的目的:
- 评估GIC对TBAD患者的临床和财务影响.
- 确定与TBAD中GIC发展相关的因素.
主要方法:
- 来自2016-2020年全国再接收数据库的TBAD初级诊断住院病例的分析.
- 将患者分为有或没有GIC的群体进行分层.
- 多变量逻辑和线性回归用于评估患者,设施和治疗因素与结果之间的关联.
主要成果:
- 在24,927名TBAD住院患者中,有2.5%患有GIC,其中24.0%需要腹部手术.
- 患有GIC的患者年轻,更常见的是男性,并且更有可能拥有医疗补助保险.
- GIC独立地与增加的住院死亡率 (aOR4.54),更长的LOS (5.80天) 和更高的成本 (41,000美元) 相相关.
结论:
- 在TBAD患者中,GIC会给患者带来重大的临床和财务负担.
- 对于早期识别和有针对性的干预措施,需要进一步的研究.
- 在这种高风险人群中,优化资源利用是必不可少的.
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