精神分裂症患者中耻辱的流行:多国系统性审查和元分析
Xianhua Wang1, Jiangli Hu1, Xiaoxia Wang1
1Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Frontiers in psychology
|November 19, 2025
概括
耻辱感影响了绝大多数精神分裂症患者,患病率因地区,年龄和疾病阶段而异. 有针对性的干预措施对于改善生活质量至关重要.
科学领域:
- 心理健康研究 心理健康研究
- 精神病学流行病学 精神病学流行病学
- 健康的社会决定因素
背景情况:
- 对精神分裂症患者来说,耻辱是治疗和康复的重要障碍.
- 了解污名的流行和影响因素对于开发有效的干预措施至关重要.
研究的目的:
- 系统地评估目前精神分裂症患者所经历的耻辱的普遍性.
- 为开发有效的干预策略提供证据,以打击耻辱.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 中进行全面的系统搜索. 这项研究将持续到2024年11月.
- 数据提取和质量评估由两名独立研究人员进行.
- 用元分析来综合包括14项涉及1872名患者的研究的结果.
主要成果:
- 在精神分裂症患者中,耻辱的综合流行率为75.3%.
- 患病率因地区 (亚洲:79.6%,非洲:49.9%),评估工具 (PDD:83.9%),出版年 (2018-2024:80.8%),年龄 (>60岁:79.5%) 和疾病阶段 (缓解:75.8%) 而有显著差异.
- 敏感性分析证实了稳定的效果大小,埃格尔的测试表明出版偏差风险低 (P=0.08).
结论:
- 污名的大量流行影响了精神分裂症患者,受人口和临床因素的影响.
- 在亚洲观察到更高的耻辱率,在PDD规模,2018年后的出版物,年龄较大的年龄组,更小的样本大小和缓解期间.
- 未来的干预措施应该在文化上适应,以减少耻辱,改善社会功能,提高患者的生活质量.
相关概念视频
Psychological and Sociocultural Causes of Schizophrenia
454
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
454
Schizophrenia
693
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
693
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
1.8K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
1.8K
Diagnostic and Statistical Manual of Mental Disorders (DSM)
981
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
981
Psychosis and Antipsychotic Drugs: Overview
786
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
786
Positive Symptoms Schizophrenia: Hallucinations and Delusions
436
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Hallucinations
Hallucinations in...
436


