胃癌与肝转移的多模式治疗:病例报告
Mengnan Li1, Gongchen Wang1, Lianyu Chen2
1Department of Medical Oncology, Affiliated Hospital of Gansu University of Traditional Chinese Medicine, Lanzhou, China.
Frontiers in oncology
|November 19, 2025
概括
结合免疫治疗的冷消化疗法对具有肝转移的晚期胃癌有希望. 这种新的方法可能会改善治疗选择有限的患者的治疗结果,这需要进一步调查.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 手术创新 在外科创新.
背景情况:
- 具有多重肝转移的晚期胃癌 (GCLM) 是一个严重的临床挑战,预后不佳.
- 对GCLM的最佳治疗策略尚未完全确定.
- 结冷处理是一种新兴的治疗方式,具有破坏瘤和免疫刺激的潜力.
研究的目的:
- 为了研究结合免疫治疗的冷消化疗法在肝转移的晚期胃癌的疗效.
- 介绍一个案例研究,强调一种新的治疗方法.
主要方法:
- 一个44岁的男性患有晚期胃腺癌和瘤迅速进展的病例呈现,尽管多次治疗.
- 在严重的肝转移时使用冷,然后用PD-1抑制剂和化疗进行联合治疗.
主要成果:
- 患者在冷和组合疗法后获得了部分反应.
- 患者经历了15个月的无进展生存期 (PFS).
结论:
- 结合免疫疗法和化疗的冷化可能为选择的GCLM患者提供可行的治疗策略.
- 这种综合方法表明了潜在的益处,并保证了进一步的临床研究.
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