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Updated: Jan 11, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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Published on: October 6, 2014

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来自BRCA1和BRCA2载体的胃上皮质含有增加的双链DNA损伤和增强生长

Kole H Buckley1, Michaela E Dungan1, Kevin Dinh1

  • 1Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

bioRxiv : the preprint server for biology
|November 19, 2025
PubMed
概括

在BRCA1和BRCA2的致病性生殖系变异增加胃癌的风险. 携带者在胃上皮和器官中显示DNA损伤和扩散的增加,这表明由于BRCA1/BRCA2脱节不足导致的早期致癌.

关键词:
这就是BRCA1的原因.这就是BRCA2的原因.造成的DNA损伤是DNA损伤.胃癌 胃癌 是一种胃癌.胃类有机物 胃类有机物

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