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相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

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相关实验视频

Updated: Jun 23, 2026

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
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树视觉系统中的映射功能使用功能性超声波成像.

Joseph B Wekselblatt1, Rohit Nayak2, Frank F Lanfranchi3,4

  • 1Department of Ophthalmology, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.

bioRxiv : the preprint server for biology
|November 19, 2025
PubMed
概括
此摘要是机器生成的。

功能性超声波成像 (fUSI) 现在以高分辨率映射树中的视觉处理. 这种技术揭示了详细的脑活动,通过桥梁动物和灵长类研究,帮助视觉研究.

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科学领域:

  • 神经科学是一个神经科学.
  • 系统神经科学 系统神经科学
  • 视觉科学科学 视觉科学

背景情况:

  • 北方树是视觉研究的新兴模型生物,在动物和灵长类动物系统之间提供了一个独特的桥梁.
  • 了解树的视觉处理需要先进的功能神经成像技术,能够提供高空间和时间分辨率.

研究的目的:

  • 适应和验证功能性超声波成像 (fUSI) 用于在清醒,头部固定的北方树中进行功能性大脑映射.
  • 在树中生成视觉皮层和相关的亚皮层结构的高分辨率功能地图.

主要方法:

  • 适应功能性超声波成像 (fUSI) 用于清醒,头部固定的北方树.
  • 利用视网膜刺激,全场噪声,运动定位器和基于对象的对比来引起视觉反应.
  • 实现了大约100μm的空间分辨率和100ms的时间分辨率用于血液动力学映射.

主要成果:

  • 在视觉处理区域 (包括皮质,上结肠和皮质下结构) 展示了强大的,特定于空间的血液动力学反应.
  • 成功地绘制了视觉系统中的视网膜组织,横向性和刺激选择模块.
  • 获得大脑血液体积 (%CBV) 的高信号噪声比率百分比变化,使单次会议功能映射高效.

结论:

  • 建立了fUSI作为一个强大而可扩展的工具,用于北方树的功能性大脑映射.
  • fUSI提供介面尺度的功能地图,补充高密度电生理学,帮助系统层面的理解视觉电路.
  • 加快树模型用于视觉研究的实用性,弥合来自动物和灵长类动物视觉系统的遗传见解.