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Updated: Jun 20, 2026

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging
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在乳腺癌细胞中映射亚型特定的PARP1 ADP-ribosylated蛋白质组

Sneh Koul1,2, Minjung Kwon1, Poulami Tapadar1

  • 1Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

bioRxiv : the preprint server for biology
|November 19, 2025
PubMed
概括

多 (ADP-ribose) 聚合酶1 (PARP1) 在乳腺癌亚型中不同调节基因表达. 这项研究揭示了亚型特定的PARP1点,影响基因调节和潜在的药物反应.

关键词:
在ADP-ribosylation (ADPRylation) 过程中,ADP-ribosylation (ADPRylation) 是一种新型的基因.乳腺癌是什么? 乳腺癌是什么?细胞生长细胞的生长.染色体重塑复杂的复杂的重建.基因调节 基因调节基因组合物 基因组合物基斯修饰酶 基斯修饰酶 基斯修饰酶PARP1 的第一部分转录 翻译 翻译转录因子是一种转录因子.

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