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Updated: Jan 11, 2026

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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CXCR1和CXCR2显示受体偏差的共享化学激素激动剂

Chanpreet Jassal1, Joseph Strawn1, Krishna Rajarathnam2

  • 1Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.

bioRxiv : the preprint server for biology
|November 19, 2025
PubMed
概括

这项研究揭示了化学因子受体 (CKR) 中的受体偏差,显示了相同的配体如何在不同的受体上触发不同的G蛋白和β-止素信号,从而影响细胞结果.

关键词:
有偏见的激进主义.化学物质化学物质是化学物质.化学因子受体 化学因子受体与G蛋白结合受体的受体是G蛋白结合的受体.受体偏差是一种受体偏差.

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