Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

APOE is a presynaptic protein that accumulates with age and modulates neurotransmitter release.

bioRxiv : the preprint server for biology·2026
Same author

NBL1 associates with renal phenotypes in mice, but partial Nbl1 reduction does not ameliorate kidney disease.

American journal of physiology. Renal physiology·2026
Same author

Spoti-find: a novel, open-source void spot assay image analysis tool.

American journal of physiology. Renal physiology·2026
Same author

Circadian Dysregulation in Aging Alters Senescence and Inflammatory Pathways in a Sex- and Time-of-Day-Dependent Manner.

bioRxiv : the preprint server for biology·2026
Same author

Hyperinnervation inhibits organ-level regeneration in mammalian skin.

Cell·2026
Same author

Astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate, and atorvastatin-telmisartan do not increase lifespan in UM-HET3 mice.

GeroScience·2026

相关实验视频

Updated: Jan 11, 2026

Real-Time Void Spot Assay
06:39

Real-Time Void Spot Assay

Published on: February 10, 2023

2.5K

Spoti-find:一个新的,开源的空点测试图像分析工具.

Cara C Hardy, Susan Sheehan, Seamus Mawe

    bioRxiv : the preprint server for biology
    |November 19, 2025
    PubMed
    概括

    Spoti-find是一个新的,开源软件,用于分析动物空点测试 (VSA). 它提供了改进的指标和用户友好的界面,增强了在临床前研究中的尿功能障碍的研究.

    科学领域:

    • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
    • 动物行为 动物行为
    • 软件开发 软件开发

    背景情况:

    • 空点测定 (VSA) 对于研究动物的尿路行为至关重要.
    • 现有的VSA分析工具缺乏全面的功能,吞吐量或可访问性.

    研究的目的:

    • 开发Spoti-find,这是一个开源的VSA图像分析应用程序.
    • 引入新的指标和用于VSA分析的用户友好的界面.

    主要方法:

    • 开发了Spoti-find,这是一个独立的应用程序,具有图形用户界面.
    • 实现手动/半自动识别,可调节的值和数据输出.
    • 引入了新的指标:空虚循环,边缘距离和基于体积的空虚区分.

    主要成果:

    • Spoti-find 显示了强大的用户间一致性和对已知的表型的敏感性.
    • 该软件准确地捕获了与现有工具高度一致的新参数.
    • 在各种数据集中验证,包括衰老和疾病模型.

    结论:

    • Spoti-find通过分析空格模式的行为上下文和空间形态学来增强VSA的解释能力.

    更多相关视频

    Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
    07:38

    Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper

    Published on: April 9, 2017

    10.4K
    Measuring the Shape and Size of Activated Sludge Particles Immobilized in Agar with an Open Source Software Pipeline
    09:27

    Measuring the Shape and Size of Activated Sludge Particles Immobilized in Agar with an Open Source Software Pipeline

    Published on: January 30, 2019

    7.4K

    相关实验视频

    Last Updated: Jan 11, 2026

    Real-Time Void Spot Assay
    06:39

    Real-Time Void Spot Assay

    Published on: February 10, 2023

    2.5K
    Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
    07:38

    Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper

    Published on: April 9, 2017

    10.4K
    Measuring the Shape and Size of Activated Sludge Particles Immobilized in Agar with an Open Source Software Pipeline
    09:27

    Measuring the Shape and Size of Activated Sludge Particles Immobilized in Agar with an Open Source Software Pipeline

    Published on: January 30, 2019

    7.4K
  • 在临床前研究中提供灵活,用户友好的平台来表型化尿功能障碍.
  • 扩大VSA对老龄化和疾病模型的研究能力.