头骨底部骨髓炎复杂化COVID-19:一种新的二次感染?
Emel Tahir1, Heval Can Bilek2, Emre Demirel1
1Department of Otorhinolaryngology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.
Journal of clinical practice and research
|November 19, 2025
概括
在免疫功能低下的患者中,COVID-19可能导致严重的耳部感染,如头骨基骨质炎. 早期成像对于COVID-19后持续的耳部泄漏至关重要,以确保及时诊断和治疗.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 关键护理医学 关键护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 流行病增加了二次感染的发生率,包括鼻粘膜炎和骨骨质炎,特别是在免疫力低下的人群中.
- 与COVID-19相关的免疫抑制和治疗可以加剧糖尿病和慢性功能衰竭等并发症,增加对严重感染的易感性.
- 外耳道中的 ангиотензин转化酶2 (ACE2) 受体可能在COVID-19相关的外耳炎中发挥作用.
研究的目的:
- 在COVID-19后的老年人,免疫抑制患者中报告两例耐治疗的外耳炎和骨骨质炎.
- 突出在标准抗生素疗法失败时管理这些感染的挑战.
- 强调在COVID-19后患有持续耳朵问题的患者考虑骨骨质炎的重要性.
主要方法:
- 关于两名患有糖尿病和慢性功能衰竭的老年患者的病例报告,他们之前接受过COVID-19治疗.
- 对抗治疗的外耳炎和骨底骨髓炎的描述.
- 包括因治疗失败而转诊进行高压氧气疗法.
主要成果:
- 两位患者都出现了严重的,耐治疗的外耳炎和骨骨质炎.
- 在这两种情况下,标准的局部和静脉注射抗生素治疗都是无效的.
- 高压氧气疗法作为一种替代治疗方式被追求.
结论:
- 在有COVID-19病史的患者中,持续的耳部泄漏保证了对骨底骨髓炎的高度怀疑指数.
- 早期和适当的成像对于迅速诊断骨底骨质炎至关重要.
- 对于耐火病例,可能需要积极的治疗,可能包括高压氧疗法.
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