眼睛结核病,抗结核预防和与眼睛结核病混的疾病:简要报告
Cagatay Karaca1, Furkan Ozer2, Duygu Gulmez Sevim1
1Department of Ophthalmology, Erciyes University Faculty of Medicine, Kayseri, Türkiye.
概括
眼结核病 (OTB) 和沙尔科毒症可能是具有挑战性的诊断,特别是当患者接受抗瘤缩因子α (抗TNF-α) 治疗时. 由于免疫抑制风险增加,对结核病的警至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
背景情况:
- 眼结核病 (OTB) 和肉类疹是脑膜炎的差异诊断.
- 抗瘤坏死因子α (抗TNF-α) 治疗越来越多地用于耐药性脑膜炎.
- 这些疾病带来了诊断挑战,特别是在非特有地区.
研究的目的:
- 突出眼结核病 (OTB) 和肉类瘤的诊断考虑因素.
- 强调在接受抗TNF-α治疗的患者中对结核病 (TB) 保持警的重要性.
- 介绍一系列案例,说明这些诊断挑战.
主要方法:
- 对八名患有OTB,潜藏性结核病或沙尔科发病的患者的病例系列审查.
- 对诊断试验结果的分析,包括QuantiFERON®-TB (QFT) 和抗酸细菌 (ARB) 试验.
- 在相关情况下,包括脑成像发现.
主要成果:
- 只有一个患者的QFT结果呈阳性.
- 只有一个病例显示出阳性ARB测试.
- 大脑成像在一个案例中是有价值的.
- 即使在非流行地区,OTB仍然是一个相关的诊断.
结论:
- 在临床检查中应考虑眼结核病.
- 增加抗TNF-α抑制剂的使用需要对免疫抑制进行监测.
- 在接受抗TNF-α治疗的患者中,对结核病风险的警至关重要.
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