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Updated: Jul 19, 2026

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
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一种基于mRNA的FimH纳米粒子疫苗对尿病原菌大肠杆菌具有高度的免疫性,在动物中具有很高的免疫性

Sandro Roier1, Roberto Adamo2, Roberto Rosini2

  • 1CureVac SE, Tübingen, Germany.

Frontiers in immunology
|November 19, 2025
PubMed
概括

针对FimH的新型mRNA疫苗有望预防由抗生素耐药性尿病原性大肠杆菌 (UPEC) 引起的复发性尿路感染 (UTIs). 在动物模型中,FimH-Ferritin mRNA疫苗表现出优越的免疫性,这表明了潜在的新疗法策略.

关键词:
在FimH中,我们在UPEC UPEC上在UPEC疫苗的疫苗.这是mRNA疫苗.纳米颗粒是一种纳米粒子.尿路感染 尿路感染泌尿病原性大肠杆菌 (E. coli) 是一种

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