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儿科社区获得性败血症的临床特征,微生物学概况和死亡率预测因素:单中心研究

Pınar Önal¹, Fatih Aygün², Berfin Ayla Hastürk Şen³

¹Department of Pediatric Infectious Diseases, İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye.

Turkish archives of pediatrics

|November 19, 2025

概括

儿童社区获得的败血症主要是由金黄色葡萄球菌引起的,死亡率为6.5%. 急性损伤和机械通风是儿童死亡的关键危险因素.

科学领域:

儿科重症监护医药儿科重症监护医药
传染病传染病传染病
微生物学微生物学

背景情况:

败血症是儿科重症监护室 (PICU) 中的主要死亡原因.
儿童在社区获得的败血症由于免疫不成熟和抗菌素耐药性而带来了独特的挑战.
了解风险因素和病原体对于改善结果至关重要.

研究的目的:

为了调查临床特征,微生物原因和治疗小儿社区获得的败血症.
确定与这些重症儿童死亡相关的风险因素.

主要方法:

对107名社区获得性败血症儿童的回顾性单中心研究,这些儿童被录入PICU.
收集的数据包括人口统计,临床状态,实验室结果和微生物学.
基于培养结果和生存的分析.

主要成果:

总的死亡率为6.5%.
金黄色葡萄球菌是最常见的病原体 (46.7%),其次是 Pseudomonas 和 Acinetobacter 种类.
死亡率与急性损伤 (AKI),机械通风和更长的通风持续时间有关.

结论:

黄金葡萄球菌是小儿社区获得性败血症的主要病原体.
AKI和机械通风是与死亡率相关的关键并发症.
婴儿早期的グラム阴性感染可能表明潜在的免疫缺陷.

关键词:

血液培养血液培养是什么?社区感染社区感染死亡率死亡率儿科的败血症有关风险因素的风险因素.

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