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瘤中介素-1β前体的一个月光功能通过RACK1-介导的动蛋白重塑促进转移

Quanzhu Chen1,2,3,4,5, Pan Wu1,2,3,4, Jing Cai6

  • 1NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China.

Nature communications
|November 19, 2025
PubMed
概括

互乐金-1β的非活性前体 (Pro-IL-1β) 通过稳定RACK1.1,驱动头癌转移. 一种天然化合物Q3MG降解了Pro-IL-1β,抑制了癌症的传播.

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