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Updated: Jan 11, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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基因组翻倍作为卵巢癌演变的动态驱动因素:从单细胞测序的见解

Tianjiao Zhao1, Tianshi Zhao2, Dengyu Dong3

  • 1Clinical School, North Henan Medical University, Xinxiang, Henan, 453003, China. tian.jiao.856@163.com.

Journal of ovarian research
|November 19, 2025
PubMed
概括

全基因组倍化 (WGD) 通过促进染色体不稳定性和免疫抑制,推动卵巢癌的瘤进化. 这一宏观进化事件为高度血清性卵巢癌 (HGSOC) 提供了新的生物标志物和治疗点.

关键词:
染色体的不稳定性高度的血清性卵巢癌.免疫抑制是一种免疫抑制.瘤的进化过程整个基因组的翻一番.

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