在早产婴儿的呼吸暂停的定义和监测方法:一个范围审查
Emily Jeanne1, Shasha Lv2, Eva Sénéchal1
1Department of Medicine, Division of Clinical and Translational Research, McGill University, Montreal, QC, Canada.
Pediatric research
|November 19, 2025
概括
对于早产婴儿的呼吸暂停的最佳定义和监测实践是未知的. 本次审查强调了当前方法和定义的显著变化,强调需要标准化指导方针和增强的监测工具.
科学领域:
- 新生儿医学 新生儿医学
- 呼吸系统生理学 呼吸系统生理学
- 医疗器械技术 医疗器械技术
背景情况:
- 呼吸暂停在早产婴儿中很常见,但没有建立最佳的定义和监测实践.
- 目前的临床方法和对此种人群中呼吸暂停的定义缺乏标准化.
- 这种变化影响了临床护理和研究准确性.
研究的目的:
- 对用于监测早产婴儿呼吸暂停的临床方法进行范围审查.
- 描述新生儿文献中使用的呼吸暂停的各种定义.
- 识别差距,并告知对标准化的需要.
主要方法:
- 在主要数据库 (Cochrane,EMBASE,MEDLINE,Web of Science) 中进行了全面的文献搜索.
- 包括在过去25年内发表的研究,重点关注早产婴儿的呼吸暂停监测.
- 数据提取的重点是参与者的细节,监控设备和呼吸暂停的定义.
主要成果:
- 审查了176项研究,其中使用了12种用于呼吸努力的设备和7种用于呼吸空气流量监测的设备.
- 空气流监测方法在灵敏度和可行性方面存在局限性.
- 在164个呼吸暂停定义中,67%仅依赖休息时间,而33%包括心肌梗塞和/或氧气不和.
结论:
- 在当前文献中,呼吸暂停检测方法和定义存在显著的变化.
- 迫切需要加强监测工具和标准化指导方针来定义早产婴儿的呼吸暂停.
- 建议在未来的研究中采用多模式和纵向监测方法,以捕捉呼吸暂停的复杂性.
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