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Updated: Jan 11, 2026

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丁丁达尼布通过促进铁亡和调节ATF4/SLC7A11/GSH轴来增强瘤细胞的辐射敏感性

Chunya Li1, Aifeina Aili1, Qingqing Yu1

  • 1Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Cancer biology & medicine
|November 19, 2025
PubMed
概括

与放射治疗相结合的宁泰达尼布可以通过促进铁亡来增强抗瘤效果. 这种组合针对ATF4通路,为固体瘤提供低毒性治疗策略,克服放射性耐药性.

关键词:
在ATF4中使用ATF4.尼丁达尼比尼是什么意思在 SLC7A1111 中.铁性化 (ferroptosis) 是一种辐射疗法 辐射疗法

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