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Updated: Jan 11, 2026

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转基因分析揭示了DNA甲基化和转录因子在肥胖肝脏蛋白质表达中的作用

Hideki Maehara1, Atsushi Hatano1,2, Masaki Shirai1

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

NPJ systems biology and applications
|November 19, 2025
PubMed
概括

肥胖通过改变蛋白质表达来改变肝功能. 虽然转录因子的变化是关键的,但肥胖肝脏的特定蛋白质减少与DNA甲基化和减少Hnf4a有关.

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