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Updated: Jan 11, 2026

Efficient and Site-specific Antibody Labeling by Strain-promoted Azide-alkyne Cycloaddition
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在工程化费里丁上,局部定向的铁酶结合保留了免疫识别

Margarida Q Rodrigues1,2, Mónica Thomaz1,2, Ricardo A Gomes1,2

  • 1iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901, Oeiras, Portugal.

Scientific reports
|November 19, 2025
PubMed
概括

费里纳米颗粒被设计为精确的抗原显示,使用铁酶介导的氨酸结合. 这种强大的平台使得基于蛋白质的先进疫苗和生物治疗药物的开发成为可能.

关键词:
抗原显示显示器显示抗原.生物结合的生物结合费里纳米颗粒 Ferritin纳米粒子介导催化作用的催化作用纳米技术纳米技术泰罗西纳酶的使用方法疫苗的研发工作正在进行中.

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Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
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