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Updated: Jan 11, 2026

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl
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A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl

Published on: November 28, 2014

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开发Granzyme A启动光活动型探头的开发

Sebastian M Malespini1, Muhammad Kazim1, Euna Yoo1

  • 1Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.

Chembiochem : a European journal of chemical biology
|November 19, 2025
PubMed
概括

研究人员开发了新的探针来检测Granzyme A (GzmA) 活性,这对于理解其在癌症免疫和炎症中的双重作用至关重要. 这些工具使生物系统中GzmA的精确可视化.

关键词:
基于活动的探测器.一个粒酶A的粒酶A.免疫力是一种免疫力.这是光学成像.蛋白质酶蛋白质酶是一种蛋白质.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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