相关实验视频

Updated: Jun 27, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
11:38

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC

Published on: May 10, 2016

12.7K

使用hERG测定方法评估正控药物的统计方法

Yu-Ting Weng1, Dalong Huang1

  • 1Division of Biometrics VI, Office of Biostatistics, Office of Translational Sciences, CDER, FDA, Maryland, USA.

Journal of biopharmaceutical statistics
|November 19, 2025
PubMed
概括

一个新的统计框架量化了人类以太-a-go-go相关基因 (hERG) 测试相似性,解决了实验室间的变异性. 这种方法有助于预测药物诱导的QT间隔延长,确保临床试验前的患者安全.

关键词:
在 ICH E14 S7bb 中.同等性测试等同性的测试.赫尔格安全测定

更多相关视频

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay07:52

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

Published on: September 10, 2018

9.2K
Author Spotlight: Scalable Drug Screening Protocol for Efficient Discovery of M. abscessus Treatments07:50

Author Spotlight: Scalable Drug Screening Protocol for Efficient Discovery of M. abscessus Treatments

Published on: October 25, 2024

2.3K

相关概念视频

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...