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Updated: Jul 10, 2026

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

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对多囊卵巢综合征和相关疾病的实验动物模型的洞察力

Surabhi B Patil1, Yogesh A Kulkarni2

  • 1Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Deemed to be University, V. L. Mehta Road, Vile Parle (W), Mumbai, 400056, Maharashtra, India.

Reproductive sciences (Thousand Oaks, Calif.)
|November 19, 2025
PubMed
概括

动物模型对于多囊性卵巢综合征 (PCOS) 研究至关重要,但目前的模型难以完全复制人类生理学. 改进这些模型是更好地理解和治疗PCOS的关键.

关键词:
动物模型动物模型心脏功能障碍是因为心脏功能障碍.循环节律失常症 循环节律失常症神经内分泌功能障碍是神经内分泌功能障碍.多囊性卵巢综合征多囊性卵巢综合征

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Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...