与无法实现夜间血压控制相关的因素
Tatsuya Maruhashi1, Yoshihiko Kinoshita2, Ryoji Ozono3
1Department of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
在服用药物的患者中,夜间血压升高 (BP) 很难正常化. 较高的夜间血压和利尿剂使用与治疗失败有关,这表明需要个性化护理.
科学领域:
- 心脏病学 心脏病学
- 高血压管理 高血压管理
- 临床研究 临床研究
背景情况:
- 广岛NOCTURNE研究研究了已经服用抗高血压药物的患者的夜间升高血压 (BP) 的正常化.
- 家庭血压监测 (HBPM) 用于评估BP.
- 这次子分析的重点是导致无法使夜间高血压正常化的因素.
研究的目的:
- 确定与无法使夜间高血压正常化相关的因素.
- 了解治疗患者的夜间高血压管理中的挑战.
主要方法:
- 包括在基线夜间高血压患者 (平均夜间缩血压≥120 mmHg).
- 进行了为期六个月的干预,以夜间血压测量为指导.
- 治疗决定取决于医生.
主要成果:
- 46.7%的患者未能使夜间血压正常化 (<120 mmHg).
- 较高的基线夜间缩血压和基线尿剂使用与治疗失败有显著的关联.
- 糖尿病呈现出与正常化失败相关的趋势.
结论:
- 无法使夜间高血压正常化与基线夜间血压升高和利尿剂使用有关.
- 糖尿病也可能导致治疗耐药性.
- 个性化治疗策略对于服用利尿剂或糖尿病患者至关重要.
更多相关视频
04:37Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
05:16Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
相关概念视频
Factors affecting Blood pressure
Physiological Factors:
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Errors occurring during blood pressure monitoring
Several factors...
Hypertension and Regulation of Blood Pressure
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Measurement of Blood Pressure
