针对创伤后应激障碍症状的在线指导书面暴露疗法:随机对照试验
Muyang Li1, Ye Zhao1,2, David Rosenfield3
1School of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, and Key Laboratory of Machine Perception (Ministry of Education), Peking University, Beijing, China.
Psychotherapy and psychosomatics
|November 19, 2025
概括
在低资源地区,指导性书面暴露 (GWE) 有效地减少了PTSD,抑郁症和失眠症状. 这种在线治疗为缺乏服务的地区的创伤后应激障碍 (PTSD) 患者提供了有希望的治疗方法.
科学领域:
- 心理健康 心理健康
- 临床心理学 临床心理学
- 数字治疗学数字治疗学
背景情况:
- 有效的创伤后应激障碍 (PTSD) 治疗机会在资源较低的地区 (LRR) 是有限的.
- 开发可扩展和可访问的干预措施对于全球心理健康至关重要.
- 在线疗法为弥合治疗差距提供了一个潜在的解决方案.
研究的目的:
- 评估在线治疗指导书面暴露 (GWE) 的有效性,以减少PTSD症状.
- 为了将GWE与满足PTSD标准的成年人最小接触控制 (MCC) 进行比较.
- 评估GWE对LRR抑郁症和失眠严重性的影响.
主要方法:
- 一项随机对照试验对95名在中国被诊断患有PTSD或下值PTSD的成年人进行.
- 参与者被分配到GWE或MCC,在治疗前,治疗后和1,3和6个月的随访期间进行评估.
- 主要结局包括DSM-5 (PSSI-5) 的PTSD症状量表-采访和DSM-5 (PCL-5) 的PTSD检查清单,由盲目评估者进行评估.
主要成果:
- 与MCC相比,GWE在1个月后显示PSSI-5和PCL-5得分的显著降低 (分别d = -0.74和d = -0.79).
- 在GWE组中,更高的百分比的参与者在1个月后显示出可靠的PTSD症状变化 (65%对37%).
- 此外,GWE还导致抑郁症和失眠严重程度的显著降低,效果持续长达6个月.
结论:
- 指导书面暴露 (GWE) 是一个有效的在线干预,用于低资源地区的创伤后应激障碍患者.
- GWE提供了一个可扩展和可访问的治疗选择,以解决服务不足的人群中未得到满足的心理健康需求.
- 这些发现支持将数字疗法纳入全球精神卫生保健战略.
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