商业面罩中的白银生物制剂和复合材料的表征,对风险评估有影响
Charlotte Wouters1, Eveline Verleysen1, François-Xavier Ouf2
1Trace Elements and Nanomaterials, Sciensano, Uccle, Belgium.
Journal of occupational and environmental hygiene
|November 19, 2025
概括
由于潜在的毒性,面膜中的银生物制剂的表征至关重要. 研究人员确定了各种银纳米颗粒和复合材料,强调了考虑共同暴露的全面安全评估的必要性.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
- 毒理学 毒理学 毒理学
背景情况:
- 基于银的生物制剂在面膜中用于抗菌性质.
- 由于缺乏释放数据,安全评估目前依赖于安全设计原则.
- 暴露于银的潜在毒性影响需要彻底描述.
研究的目的:
- 为了识别和表征商业面罩中使用的颗粒银生物制剂.
- 为安全评估提供信息,并完善更安全的面罩的规格.
- 提供关于银的生物制剂类型,形式和尺寸的数据.
主要方法:
- 分析含有银的面膜,使用超微红外术.
- 通过扫描传输电子显微镜与能量分散式X射线光谱学 (STEM-EDX) 结合进行表征.
- 基于银的生物制剂的识别,包括纳米颗粒和纳米复合材料.
主要成果:
- 确定了各种各样的基于银的生物杀伤剂,包括金属银纳米颗粒 (NP),银盐和纳米复合材料 (例如,与二氧化,TiO2,ZnO).
- 在面具纤维上发现含银的NP,范围为3至200nm (大多为<50nm).
- 其他NP如合成无形 (SAS) 和TiO2也被观察到涂层纤维.
结论:
- 安全性评估必须考虑所有纳入的化合物和潜在的共同暴露的无有害影响水平.
- 建议对面罩进行颗粒释放研究,暴露评估和监管监督.
- 这些发现有助于完善生物杀毒面膜的安全标准.
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