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Updated: Jan 11, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
07:09

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity

Published on: January 7, 2019

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针对癌症治疗的偏酶1 (MALT1) 向:更新了结构-活性关系 (SAR) 的进展和研究

Yinglong Li1, Yanyun Hong1, Jianye Zhang1

  • 1Jiangxi Provincial Key Laboratory of Drug Design and Evaluation, School of Pharmacy, Jiangxi Science & Technology Normal University, 605 Fenglin Road, Nanchang, Jiangxi, 330013, China.

European journal of medicinal chemistry
|November 19, 2025
PubMed
概括

粘膜相关淋巴组织淋巴瘤转位蛋白1 (MALT1) 对于NF-κB信号传递至关重要,并与ABC-DLBCL有关. 本综述详细介绍了MALT1抑制剂,包括共价,全,PROTAC和探针,强调了未来药物开发的机会.

关键词:
活动活动活动.马耳他语 马耳他语分子对接是分子对接.在 NF-κBB 中.优化优化 优化优化结构与活动的关系.

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