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Updated: Jan 10, 2026

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
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试验室两阶段一个隔间倾销试验数据和吸收/配方 PBBM 建模,以解释瓦尔萨坦配方的生物等价性失败

Bárbara Sánchez-Dengra1, Alejandro Ruiz-Picazo1, Isabel Gonzalez-Alvarez1

  • 1Pharmacokinetics and Pharmaceutical Technology Area. Miguel Hernandez University, Spain.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|November 19, 2025
PubMed
概括

一种简化的"倾销试验"溶解方法有效地预测了制药配方的体内生物等价性. 这种具有成本效益的方法可以建立可靠的体外-体内相关性 (IVIVC) 和基于生理学的生物制药模型 (PBBM).

关键词:
溶解建模 溶解建模倾销试验 倾销试验弱酸是一种弱酸.在体外-体内相关性 (IVIVC)基于生理学的分区药理动力学 (PBPM) 建模.

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