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Updated: Jan 10, 2026

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mTOR在托洛二酸盐诱导的喘中调解呼吸道上皮层E-cadherin干扰

Lin Fu1, Lichang Chen2, Xianru Peng2

  • 1Department of Pulmonary and Critical Care Medicine, Guangzhou Institute of Respiratory Health, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.

Toxicology and applied pharmacology
|November 19, 2025
PubMed
概括

哺乳动物的目标拉巴胺素 (mTOR) 途径驱动了空气道上皮质E-cadherin功能障碍在二酸 (TDI) 诱导的喘中. 通过拉巴胺素抑制mTOR可以恢复E-cadherin并缓解喘症状.

关键词:
气道上皮细胞 气道上皮细胞喘 喘 是一种在E-Cadherin中使用.在mTOROR中使用mTOR.

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