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Updated: Jan 10, 2026

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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通过ASB9-CUL5 Ubiquitin Ligase进行的基基化机制

Calvin P Lin1, Nathan Lee1, Francis X Alipranti1

  • 1Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California 92092, USA.

Molecular & cellular proteomics : MCP
|November 19, 2025
PubMed
概括

安基林和SOCS盒子蛋白9 (ASB9) E3结合酶复合体准了H3和H4基因组的降解. 这项研究揭示了ASB9-CRL5在没有辅助结合酶的情况下促进了基因素降解.

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