在巴雷特食道内进行内镜性粘膜切除和内镜性亚粘膜切除
Vincent Bos1, Horst Neuhaus2, Roos E Pouw3
1Department of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, the Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands.
Gastrointestinal endoscopy clinics of North America
|November 19, 2025
概括
早期发现巴雷特食道瘤病变至关重要. 像多带粘膜切除术 (MBM) 和内镜下粘膜解剖 (ESD) 这样的内镜切除技术为治愈意图提供了有效的治疗选择.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 在巴雷特食道中早期发现瘤病变对于成功的治愈治疗至关重要.
- 内镜切除 (ER) 是治疗这些病变的主要方法,允许精确的组织学诊断.
研究的目的:
- 为了比较不同内镜切除技术对巴雷特食道的疗效和安全性.
- 根据病变特征和患者因素,为选择合适的ER技术提供指导.
主要方法:
- 审查当前的内镜切除技术,包括带辅助内镜粘膜切除 (多带粘膜切除 (MBM)) 和内镜亚粘膜切除 (ESD).
- 较小病变 (<20毫米) 的MBM和较大或更深的病变的ESD的比较.
- 对MBM和ESD的安全性和疗效结果的评估.
主要成果:
- MBM适用于快速移除较小的病变.
- ESD是一种更复杂的技术,用于对更大,更深的侵入性病变进行封锁切除.
- 无论是MBM还是ESD,都显示出类似的安全性和有效性结果.
结论:
- 在MBM和ESD之间做出选择应该是个性化的.
- 影响技术选择的因素包括病变特征,患者因素和内镜师的专业知识.
- 需要进一步的前性研究来完善治疗指南.
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