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Updated: Jan 10, 2026

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma
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向VCP通过STING稳定增强结直肠癌治疗

Hongdao Zhu1, Fujing Ge1, Jingyu Dai1

  • 1Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China.

Journal for immunotherapy of cancer
|November 19, 2025
PubMed
概括

向含瓦洛辛蛋白 (VCP) 稳定了STING蛋白,增强了干扰素基因 (cGAS-STING) 循环GMP-AMP合成酶刺激通路. 这种方法可以增强抗瘤免疫力,并克服结直肠癌 (CRC) 中的免疫疗法耐药性.

关键词:
化疗 化疗是一种化学疗法.结肠直肠癌是什么意思组合疗法是一种联合疗法.巨细胞是一个巨细胞.瘤微环境 - - 瘤微环境

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