宽动脉瘤的康尼西辅助栓塞:来自美国成功后市场研究的结果
Jason M Davies1,2, Muhammad Asif Taqi3, Alexander L Coon4
1Neurosurgery and Bioinformatics and Canon Stroke and Vascular Research Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Journal of neurointerventional surgery
|November 19, 2025
概括
科曼尼奇装置有效地治疗具有高闭塞率的宽脑动脉瘤. 这项研究表明,Comaneci辅助卷圈技术的安全性和持续有效性良好.
科学领域:
- 神经外科 神经外科
- 干预性神经辐射学
- 血管神经学 血管神经学
背景情况:
- 宽子内动脉瘤对内血管栓塞构成重大挑战.
- 科曼尼奇装置提供了一种新的桥梁解决方案,以帮助卷轴栓塞,而不会堵塞母血管.
研究的目的:
- 评估Comaneci装置在协助宽内动脉瘤的线圈栓塞方面的有效性和安全性.
- 评估动脉瘤闭塞的持久性和患者的临床结果.
主要方法:
- 康纳西辅助线圈栓塞监测研究中的成功 (SUCCESS) 是一项前性多中心研究.
- 90名患有宽内动脉瘤的患者使用Comaneci辅助卷曲进行了治疗.
- 主要终点包括手术闭塞率和24小时内发生的安全事件,出院和30天.
主要成果:
- 在手术完成时,成功的动脉瘤封闭在85.6%的病例中实现,在6个月后持续在94.7%.
- 从基线 (73%) 到6个月 (83%) 保持良好的临床结果 (mRS 0-2).
- 观察到血栓栓塞事件的低率 (5.5%,全部无症状) 和与设备相关的并发症.
结论:
- 康纳西辅助卷曲显示了宽动脉瘤的高且持久的动脉瘤闭塞率.
- 该设备具有良好的安全性,并发症最小,支持在破裂和未破裂动脉瘤中使用.
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