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Updated: Aug 17, 2026

Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice
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Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice

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向补充抑制改善了重复重复的轻度闭合头部损伤的病理和认知结果

Khalil Mallah1,2,3, Carsten Krieg3,4, Devin Hatchell1

  • 1Department of Pharmacology and Immunology, Medical University of South Carolina, Charleston, SC, USA.

Signal transduction and targeted therapy
|November 19, 2025
PubMed
概括

重复轻度关闭头部损伤 (rmCHI) 会导致与免疫细胞变化相关的认知障碍. 在受伤后补充抑制保护了这种认知衰退,显示了治疗潜力.

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相关概念视频

Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.