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Updated: Jan 10, 2026

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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通过DNA甲基转移酶Dnmt3ba介导的Integrin信号的表观遗传调节对于造血干细胞和祖细胞发育至关重要

Kang Ai1, Yue Wu1, Guixian Liang2

  • 1Key Laboratory of Experimental Teratology of the Ministry of Education, Department of Histology and Embryology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Communications biology
|November 19, 2025
PubMed
概括

在斑马鱼发育过程中,DNA甲基转移酶3ba (Dnmt3ba) 对血源性内皮细胞 (HEC) 存活至关重要. 它的缺乏会通过影响整合素信号传递引起亡,突出显示了在造血干细胞发育中的表观遗传作用.

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