在胰腺手术后的术后疼痛治疗. 一个系统审查协议与元分析和试验序列分析
Caroline D Lassen1, Sermed Ellebæk Nicolae1, Eske Kvanner Aasvang2,3
1Department of Digestive Diseases, Transplantation and General Surgery, Copenhagen University Hospital, Rigshospitalet, Denmark.
Acta anaesthesiologica Scandinavica
|November 20, 2025
概括
本系统性审查评估了胰腺手术的疼痛管理策略,包括全胰腺切除术,胰腺二切除术和远端胰腺切除术. 关于不同止痛干预措施的益处和危害的证据尚不清楚,这会影响患者的康复.
科学领域:
- 手术 手术 手术 术 术
- 麻醉学 麻醉学
- 基于证据的医学基于证据的医学.
背景情况:
- 胰腺外科手术,如胰腺双管切除术,远端胰腺切除术和全胰腺切除术是复杂的,并引起显著的疼痛.
- 有效的术后疼痛管理对于患者的流动性,减少住院时间和减少并发症至关重要.
- 目前最佳的疼痛管理策略以及各种止痛药的风险/益处尚未明确.
研究的目的:
- 系统地审查在接受大胰腺切除的成年患者中止痛干预措施的益处和危害.
- 综合总体胰腺切除术,胰腺二切除术和远端胰腺切除术后疼痛管理的证据.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 搜索了Medline,EMBASE和CENTRAL的随机临床试验,将止痛干预措施与对照进行比较.
- 使用ROB2评估偏差风险,进行试验顺序分析,并使用GRADE评估证据质量.
主要成果:
- (等待审查完成) 本部分将详细介绍关于不同止痛干预措施的有效性和安全性的元分析结果.
- (在审查完成之前) 结果将与证据质量的GRADE评估一起提交.
结论:
- (等待审查完成) 该审查将提供关于胰腺手术最佳止痛策略的见解.
- (在审查完成之前) 调查结果将为临床实践提供有关各种疼痛管理选择的益处和危害的信息,以改善患者的治疗结果.
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