在服用抗高脂药物的患者中出现抑郁和焦虑:沙特跨截面研究

相关实验视频

Updated: Jan 10, 2026

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Mohammed A Aljaffer¹, Ahmad H Almadani¹, Abdullah N Alassiri²

¹Department of Psychiatry, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

|November 20, 2025

概括

抗高血脂药物的使用与沙特阿拉伯的抑郁率更高有关. 对于服用这些药物的患者,特别是睡眠问题或吸烟者,建议进行常规的心理健康查.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
药理学药理学是指药理学的学科.

背景情况:

抗高脂药物 (AHLM) 在全球范围内被广泛使用.
在沙特阿拉伯,AHLM的神经精神病学的副作用尚未得到充分研究.
在AHLM患者中评估焦虑和抑郁的患病率至关重要.

研究的目的:

为了确定焦虑和抑郁症状在患者处方AHLM在沙特阿拉伯的患病率.
调查AHLM使用与神经精神病症状之间的关联.
在这个人群中识别与焦虑和抑郁相关的危险因素.

主要方法:

在沙特阿拉伯利雅得的一家三级护理医院进行的横截面研究.
在接受AHLM的373名成年参与者中,使用方便抽样进行了招募.
经过验证的问卷,包括GAD-7和PHQ-9,评估了焦虑和抑郁症状.

主要成果:

焦虑症状 (GAD-7 ≥10) 的患病率为13.94%;抑郁症状 (PHQ-9 ≥10) 的患病率为15.82%.
使用AHLM与抑郁症状 (P=0.034) 有显著的关联,但与焦虑症没有关联.
睡眠问题和身体不活动与焦虑和抑郁症有显著的联系.

结论:

在沙特人口中,使用AHLM与抑郁症状的可能性增加有关.
应将心理健康查纳入AHLM患者的护理,特别是那些有睡眠障碍或吸烟习惯的患者.
需要进一步的研究来探索这些协会背后的机制.

关键词:

沙特阿拉伯沙特阿拉伯沙特阿拉伯这是一种抗滑脂性抗体.焦虑是一种焦虑.抑郁抑郁症抑郁症抑郁症是一种

更多相关视频

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

相关概念视频

Atherosclerosis III: Management

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...

Lipids: Dietary Sources and Requirements

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...