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Updated: Jan 10, 2026

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核DAB2IP通过激活PLK1介导的HBO1酸化来调节DNA复制的启动

Zeng-Fu Shang1, Lan Yu2, Ciara Newman1

  • 1Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas TX 75390, United States.

Nucleic acids research
|November 20, 2025
PubMed
概括

禁用同源2相互作用蛋白 (DAB2IP) 促进DNA复制的启动,并保持基因组的稳定性. 它与HBO1的相互作用和CDK1的酸化对DNA复制和细胞平衡至关重要.

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