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Updated: Jan 10, 2026

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长单链DNA具有特定站点的修改,以实现单基分辨率表观遗传学

Chenyou Zhu1, Yin Xu2, Ziyang Hao3

  • 1Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P.R. China.

Angewandte Chemie (International ed. in English)
|November 20, 2025
PubMed
概括

研究人员开发了一种合成改性长单链DNA (ssDNA) 的方法. 这使得DNA甲基化模式的精确分析成为可能,揭示了5-甲基氨酸密度如何影响表观遗传动力学和维护.

关键词:
5 - - 甲基细胞因.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.长长的单链DNA.通过单一基准进行解决方案.特定地点的修改.

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