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临床,皮肤镜和组织病理学研究下肢斑块性色素的研究
Kalaiarasi Murugan1, Devinder Mohan Thappa1, Malathi Munisamy1
1From the Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Indian journal of dermatology
|November 20, 2025
概括
这项研究发现,印度大多数下腿色素病例都是低色素的,其最常见的原因是异常性大肠腺低色素症. 皮肤显微镜有助于诊断这些疾病.
科学领域:
- 皮肤病学 皮肤病学
- 皮肤病理学 皮肤病理学
背景情况:
- 下腿的斑块性色素化涉及皮肤颜色的变化,包括多色素化,低色素化或脱色.
- 皮肤镜是一种有价值的非侵入性工具,用于评估下腿色素,弥合临床和组织学评估.
- 这项研究代表了重要的贡献,可能是印度关于下腿色素的第一份报告.
研究的目的:
- 为了调查不齐下腿色素的临床,皮肤镜和组织病理学特征.
- 在受研究的人群中,确定腿部下部的低颜色和高颜色的主要原因.
主要方法:
- 一项涉及150名患有下腿色素的成年患者的横截面描述性研究.
- 数据收集包括详细的患者病史,皮肤学检查,皮肤镜检查和皮肤活检以检查组织病理学.
- 在2022年3月至2023年12月期间,JIPMER的皮肤病门诊部 (OPD) 招募了患者.
主要成果:
- 在下腿色素中,低色素 (84.66%) 比高色素 (15.33%) 更为普遍.
- 异形性质的状肌肤低调 (IGH) 是导致低颜色的首要原因 (48.81%),其次是白风 (25.19%) 和后炎性脱色 (22.65%).
- 颜色紫色皮肤病 (PPD) 是最常见的过色素的原因 (52.17%),其次是后炎性过色素 (43.47%).
结论:
- 低颜色系疾病构成了大部分下腿色素病例,其中IGH占主导地位.
- 皮肤镜检查白风和后炎性脱色素的发现显示了相似之处.
- 后发性皮肤病和后炎性多色素是导致下肢多色素障碍的关键原因.
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