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Updated: Jan 10, 2026

Developing a Rat Model for Bipolar Disorder
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克洛扎宾药物相互作用和双极性障碍的个性化剂量:一种基于模型的精确剂量方法

Yue Zhang1, Jie Wang1, Xue Tian1

  • 1Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, People's Republic of China.

Drug design, development and therapy
|November 20, 2025
PubMed
概括

基于模型的精确剂量 (MIPD) 确定了双相情绪障碍 (BD) 患者中克洛扎宾和皮克隆或皮酸盐之间的药物相互作用 (DDI). 这项研究提供了针对体重的克洛扎剂量建议,以提高安全性和有效性.

关键词:
双相情感障碍是双相情感障碍的一种疾病.克洛扎类药物 克洛扎类药物药物 药物相互作用索尔皮德姆酸酸盐是什么佐皮克隆是不是可以

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