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Updated: Jan 10, 2026

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基于昆的神经皮林-1对抗剂表现出纯抗体特征,并阻断血管内皮生长因子诱导的疼痛

Sara Hestehave1, Silvia Dragoni2, Philip Fallon3

  • 1Department of Molecular Pathobiology, College of Dentistry, New York University, New York, New York 10010, United States.

ACS pharmacology & translational science
|November 20, 2025
PubMed
概括

一种新的化合物EG01449 (12h) 作为神经皮林-1 (NRP1) 抗剂,可减少疼痛信号传递. 这一发现通过向血管内皮生长因子 (VEGF) 途径,为慢性疼痛提供了一种新的治疗策略.

关键词:
在NRP1中,NRP1是指NRP1.在VEGF中,VEGF是VEGF.这是一种抗可感的抗可感药.慢性疼痛是一种慢性疼痛.这是一种神经皮林.

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