在高血压的老年人中使用β抑制剂和抑郁症状:一个多中心研究
Mayra Valdivia-Herrera1, P Alejandra Goicochea-Romero1, Christopher Butler Vallejo2
1. CHANGE Research Working Group, Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Peru. Universidad Científica del Sur CHANGE Research Working Group Carrera de Medicina Humana Universidad Científica del Sur Lima Peru.
Archivos peruanos de cardiologia y cirugia cardiovascular
|November 20, 2025
概括
在患有高血压的老年人中,β-阻断剂的使用与抑郁症状无关. 然而,虚弱和较低的教育水平增加了这种人群中抑郁症的风险.
科学领域:
- 老年病的医生 老年病的医生
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
背景情况:
- 高血压 (HTN) 是老年人中普遍存在的疾病.
- 抗高血压药物,包括β抑制剂,通常被处方.
- 贝塔抑制剂对心理健康的潜在影响,特别是抑郁症状,需要在这个人口群体中进行调查.
研究的目的:
- 确定是否存在使用β-阻断剂和在被诊断为高血压的老年人中出现抑郁症状之间的联系.
- 确定其他可能与该患者群体中抑郁症状相关的因素.
主要方法:
- 对149名高血压的老年人进行了一项横截面观察研究.
- 使用PHQ-9问卷评估抑郁症状.
- 统计分析包括双变量测试和Poisson回归来计算流行率 (PR).
主要成果:
- 在使用β-阻断剂和抑郁症状之间没有发现显著的关联 (PR:1.09;95%CI:0.70-1.69).
- 虚弱的增加与抑郁症状的更高风险显著相关 (PR:5.72;95% CI:2.17-15.0).
- 更高的教育程度 (技术或大学) 与抑郁症状的风险较低有关 (PR:0.43;95% CI:0.25-0.74).
结论:
- 贝塔抑制剂治疗似乎与患有高血压的老年人抑郁症状无关.
- 虚弱和较低的教育水平是高血压老年患者抑郁症的重要风险因素.
- 对这一群体的情绪健康的综合评估应该考虑除了药物使用之外的因素,例如脆弱性和教育.
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