人类CD4和CD8记忆T淋巴细胞的甲基组揭示了组织特异性的表观遗传特征,用于维护和召回功能

Xiangyi Deng1, Weijie Du1, Gilles Gasparoni2

  • 1Department of Cell Biology, Deutsches Rheuma-Forschungszentrum Berlin, Institute of the Leibniz Association, Berlin, Germany.

Immunity & inflammation
|November 20, 2025
PubMed
概括

组织内存T细胞表现出独特的DNA低甲基化模式,对于它们的功能和维护至关重要. 这项研究揭示了表观遗传特征,解释了这些免疫细胞如何在特定组织中召回和持续存在.

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