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传统的内血管治疗和流量转移器用于未破裂的小和中型眼膜段动脉瘤

Kefeng Liu¹, Yong Sun², Fang Liu¹

¹Digital Intelligence Neural Research Laboratory, Department of Neurosurgery, The Second People's Hospital of Changzhou, The Third Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.

Frontiers in neurology

|November 20, 2025

概括

传统的内血管治疗 (CET) 显示,对于中小型内动脉瘤,完全封闭率与流量转移器 (FD) 相似. 然而,CET提供了更好的安全性,特别是在老年患者中.

科学领域:

神经外科神经外科
干预性放射学干预性放射学
血管神经学血管神经学

背景情况:

流量转移器 (FD) 与中小型内动脉瘤的常规内血管治疗 (CET) 的比较疗效和安全性尚未得到充分证实.
偏眼段动脉瘤 (PSA) 是内血管干预的常见目标.

研究的目的:

为了比较FD和CET在治疗中小和中型PSA中的疗效和安全性.
为在PSA治疗中做出明智的临床决策提供证据.

主要方法:

2018年1月至2023年12月期间对未破裂的小至中型 (≤10毫米) PSA患者进行多中心回顾性队列研究.
在CET和FD组之间对初级疗效 (完全封闭率) 和安全性 (并发症率) 终点进行比较.
进行了倾向分数匹配 (PSM) 和子组分析,以确保结果的稳定性并确定影响因素.

主要成果:

总共分析了688个PSA (595个CET,93个FD),平均随访时间为12.6个月.
初始完全封闭率在CET (98.2%) 时高于FD (66.7%),但累计封闭率在时间上没有显著差异 (p=0.261).
FD组的整体并发症率较高 (12.0%对1.1%,p=0.007),尽管长期功能结果没有显著影响. 在65岁以上的患者中,CET的益处更大.

结论:

小到中型PSA的完全封闭率在CET和FD疗法之间没有显著差异.
需要仔细考虑FD的程序安全性,CET在老年患者中显示出更明显的治疗益处.

关键词:

有效性和安全性.血管内治疗血管内治疗流量转移器是一个流量转移器.帕拉眼部段动脉瘤倾向性得分匹配的比分匹配

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