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从1990年到2021年,新生儿败血症死亡率和可归因的危险因素的全球趋势
Haofeng Guan1,2, Xiaocha Liang2, Yuanhao Liang3
1Department of Pediatrics, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Journal of paediatrics and child health
|November 20, 2025
概括
全球新生儿败血症死亡率下降,但在低收入地区增加. 孕期短和出生体重低是关键的风险因素,突出了改善医疗保健基础设施的需要.
科学领域:
- 全球卫生健康 全球卫生健康
- 新生儿健康新生儿健康
- 流行病学 流行病学
背景情况:
- 新生儿败血症,包括早期和晚期发病的形式,是全球婴儿死亡的一个重要原因.
- 了解时间趋势和风险因素对于有效的公共卫生干预至关重要.
研究的目的:
- 从1990年到2021年,分析早期和晚期新生儿败血症的全球,区域和国家死亡率趋势.
- 确定和量化新生儿败血症死亡的可归因风险因素.
主要方法:
- 利用2021年全球疾病负担研究 (GBD) 的新生儿败血症死亡和风险因素归因的数据.
- 通过估计死亡率的每年百分比变化来评估时间趋势.
主要成果:
- 在2021年,全球死亡人数为136,040 (早期发病) 和70,411 (晚期发病).
- 总体而言,死亡率下降,但在社会人口指数 (SDI) 较低的地区,特别是撒哈拉以南非洲,死亡率上升.
- 孕期短和出生体重低是主要原因,分别占死亡人数的29.6%和66.3%.
结论:
- 新生儿败血症仍然是一个关键的全球卫生问题,特别是在SDI低的地区.
- 需要紧急干预,专注于早产,低出生体重和加强医疗保健系统.
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