相关实验视频
Updated: Jan 10, 2026

11:12
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
23.0K
深度大脑刺激对帕金森病自主症状的影响:一个范围广泛的综述
John Chen1, Jonathan Silva1, Aditya Goyal1
1Department of Neurosurgery, Albany Medical Center, Albany, NY, USA.
Movement disorders clinical practice
|November 20, 2025
概括
深度大脑刺激 (DBS) 显示了对帕金森病的潜力.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 医疗器械 医疗器械
背景情况:
- 自主功能障碍是帕金森病 (PD) 的重要非运动症状,影响生活质量.
- 常见的自主性症状包括胃肠道,心血管,呼吸道,温度调节和尿道失调.
- 深度大脑刺激 (DBS) 已被确立为PD运动症状,但其对自主功能障碍的影响尚不清楚.
研究的目的:
- 系统地审查和绘制有关DBS对帕金森病自主症状影响的现有证据.
- 为了确定有关DPD在PD中各种自主功能障碍的DBS疗效的知识差距.
主要方法:
- 进行了全面的电子文献搜索.
- 搜索遵循乔安娜·布里格斯研究所对范围审查的方法框架.
- 从最初的825个独特参考资料中,包括了57项研究.
主要成果:
- 在五个自主领域报告了证据:胃肠道 (37项研究),心血管 (40),呼吸 (4),温度调节 (13) 和尿道 (25).
- 调查结果异质,受到不一致的结果指标的限制,随访时间多样化,缺乏针对目标的具体报告.
- DBS在胃肠道和心血管领域显示出潜在的益处,但整体疗效尚不清楚.
结论:
- 深度大脑刺激可能对帕金森病中的某些自主症状,特别是胃肠道和心血管症状有好处.
- 对于尿道,温度调节和呼吸系统症状的DBS疗效需要进一步研究.
- 标准化,前性研究与验证的自主评估工具和详细的刺激参数报告是必要的,以澄清DBS的作用.
关键词:
帕金森病的疾病.自主功能障碍的自主功能障碍.心血管疾病的心血管疾病深度大脑刺激 - - 深度大脑刺激在胃肠道上,胃肠道.其他非运动症状.呼吸道 呼吸道 呼吸道范围审查 范围审查审查温度调节器的使用方法尿道 尿道 尿道 尿道更多相关视频
07:14A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test
Published on: May 31, 2016
15.3K
14:14Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
Published on: August 12, 2018
9.3K
相关概念视频
Parkinson's Disease: Treatment
953
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
953
Parkinson's Disease: Overview
1.7K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.7K
Neural Regulation
43.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.0K