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Updated: Jan 10, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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PolED:在人类中报告的POLE和POLD1变体的功能研究的手动策划数据库

Lev Tsarin1, Polina V Shcherbakova1

  • 1Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198, United States.

Database : the journal of biological databases and curation
|November 20, 2025
PubMed
概括

一个新的数据库,PolED,整合了POLE/POLD1基因变异的功能数据. 本资源阐明了这些DNA聚合酶突变对癌症发展和治疗反应的影响.

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