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Updated: Jan 10, 2026

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
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超越扩张:瘤脱皮是改善淋巴瘤中CAR T细胞潜力的关键

Philipp M Altrock1

  • 1Department of Hematology and Oncology, Clinical Research Unit CATCH-ALL, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.

Blood cancer discovery
|November 20, 2025
PubMed
概括

在仿真抗原受体 (CAR) T细胞疗法之前减少瘤负担可以提高大B细胞淋巴瘤的缓解率. 这项研究模拟了CAR T细胞动态,以优化治疗策略.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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