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使用upadacitinib成功治疗与多种系统性炎症疾病相关的托法西提尼布耐药性硬化症

Kodai Yuge1, Nobuyo Yawata2,3,4, Kenichiro Asahara1

  • 1Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Immunological medicine
|November 20, 2025
PubMed
概括

雅努斯酶抑制剂 (JAKi) 在耐火性硬化症方面表现有前途. 一名患有类风湿性关节炎和性结肠炎的患者在非选择性JAKi失败后,通过选择性JAK1抑制剂实现了缓解.

关键词:
安卡 ANCA 的时间.这是一种JAK抑制剂.耐火性硬化性炎症 耐火性硬化症类风湿性关节炎 类风湿性关节炎有选择性的JAK抑制剂.托法西提尼布 (tofacitinib) 是一种性结肠炎是一种在此之前,upadacitinib 已经在使用中.

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