癌症治疗史与冠状动脉炎症之间的关联
Nariko Tsukamoto1, Ayako Kunimura1, Shimpei Kuno1
1Department of Cardiology, Aichi Medical University, Nagakute, Aichi, Japan.
JACC. Advances
|November 20, 2025
概括
癌症史与冠状动脉炎症的增加有关,这是动脉样硬化的一个关键因素. 这种风险在最近接受癌症治疗的患者中特别高,突出了对心血管监测的需求.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 确立了癌症史与心血管事件增加之间的联系.
- 冠状动脉炎症是动脉样硬化斑块发展的关键因素.
研究的目的:
- 调查癌症史与冠状动脉炎症之间的独立关联.
- 评估冠状动脉炎症使用周围血管脂肪衰减指数 (FAI).
主要方法:
- 包括1141名接受冠状动脉计算机断层扫描血管造影的患者.
- 通过周血管脂肪衰减指数 (FAI) 量化冠状动脉炎症.
- 使用多变量波桑回归来分析癌症史和高FAI之间的关系,调整心血管风险因素.
主要成果:
- 癌症患者的高FAI患病率显著增加 (RR: 1.56).
- 癌症治疗后5年内患者与高FAI的相关性更高 (RR:1.70).
- 在治疗后≥5年的患者中没有发现显著的关联.
结论:
- 癌症史与升高的冠状动脉炎症有显著的关联.
- 最近的癌症治疗史是这种关联的一个关键因素.
- 研究结果表明,癌症幸存者,特别是最近接受治疗的人,心血管风险增加.
相关概念视频
Coronary Artery Disease V: Interprofessional Care
206
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
206
Coronary Artery Disease I: Introduction
857
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
857
Cancer Survival Analysis
633
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
633
Coronary Artery Disease II: Pathophysiology
348
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
348
Psychoneuroimmunology: Diabetes and Cancer
417
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
417
Cancer Prevention
7.6K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
7.6K


