为严重急性呼吸衰竭接受体外膜氧化治疗的成年人使用气道清除技术:一个范围审查协议
Tom Lunn1,2, Ema Swingwood3,4, Hannah Cochrane5
1Diagnostics and Therapies, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK thomas.lunn@uhbw.nhs.uk.
BMJ open
|November 20, 2025
概括
本范围审查检查了严重急性呼吸衰竭 (SARF) 外体膜氧化 (ECMO) 患者的气道清除技术. 它综合了当前的证据,以指导ECMO呼吸护理的最佳实践和未来研究.
科学领域:
- 临界护理医学 临界护理医学
- 呼吸系统疗法 呼吸系统疗法
- 证据综合 证据综合
背景情况:
- 患有严重急性呼吸衰竭 (SARF) 的体外膜氧化 (ECMO) 患者因疾病严重程度和通风策略而面临严重的呼吸道清除挑战.
- 在ECMO中,有限的潮体积和流量阻碍了分泌物调动,影响了患者的治疗结果.
- 缺乏关于当前空气通道清除实践,其理由和ECMO患者的结果的综合证据.
研究的目的:
- 在接受ECMO治疗SARF的成年患者中对呼吸道清除干预措施进行范围审查.
- 绘制干预类型,它们的参数,生理学理由和报告结果的地图.
- 识别安全考虑和当前实践的变化.
主要方法:
- 该审查遵循了乔安娜·布里格斯研究所的方法和PRISMA-Scoping的指导方针.
- 在多个数据库 (Embase,Emcare,Medline,CINAHL) 和灰色文献中进行了全面的搜索.
- 两位独立审查员选了研究,提取了数据,并使用描述性统计和定性内容分析合成了发现.
主要成果:
- 该部分在审查完成后将被填写.
- 预期的发现包括各种空气通道清理干预措施的地图及其报告的影响.
- 将突出实践中的差异和识别的知识差距.
结论:
- 这次审查将为SARF提供ECMO中气道清理的全面概述.
- 预计这些发现将为临床实践提供信息,并指导未来的研究,以优化呼吸系统护理.
- 结果将为制定基于证据的空气道管理指南奠定基础,用于这种脆弱的患者群体.
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